About

Pangas Laboratory

Ovarian Biology, Oocyte Quality, Infertility, and Reproductive Disease

The Pangas Laboratory at Baylor College of Medicine studies the genetic and molecular mechanisms that regulate ovarian function, oocyte quality, fertility, and reproductive disease.

Our work uses mouse genetics, reproductive physiology, molecular biology, patient-linked samples, and omics approaches to define how reproductive tissues develop, function, and fail in disease.

Research Areas:

  • Ovarian reserve formation & maintenance
  • Oocyte quality and reproductive aging
  • TGFB and BMP signaling in reproductive tissues
  • SUMOylation, NEDDylation, and proteostasis in oocytes
  • Granulosa cell tumors and reproductive cancers

Training

The lab trains undergraduates, graduate students, postdoctoral fellows, REI fellows, and research staff in reproductive biology, genetics, molecular biology, and translational research

Contact

Prospective trainees may contact Dr. Pangas at spangas@bcm.edu