Established in 2007 at Baylor College of Medicine, the mission of the Pangas Lab is to decrease the health burden of infertility and menopause through basic science and translationally-relevant research.
Our main research focus is female reproductive biology and reproductive health. We primarily use novel genetic models to uncover genes necessary for female fertility and ovarian function. This includes developing models derived from ES cell targeting, CRISPR/Cas9 genetic engineering, and Cre-loxP recombination. Our research has uncovered a host of novel genes and pathways that control ovarian and uterine function, which when disrupted cause diseases such as primary ovarian insufficiency, infertility, polycystic ovary disease and ovarian cancer.
Additionally, we utilize patient samples typically from women with reproductive disorders such as premature ovarian failure and those undergoing assisted reproductive techniques to study key pathways. These samples are used for “omic profiling”, mutation analysis, and generation of PDX models.
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Applicants interested in graduate studies at Baylor College of Medicine, should visit the website at https://www.bcm.edu/education/schools/graduate-school-of-biomedical-sciences
Interested in Reproductive Biology Research at Baylor College of Medicine? Please visit the Center for Reproductive Biology https://www.bcm.edu/research/centers/reproductive-medicine
Like to join our NIH T32 as a postdoctoral candidate? Please click on the T32 Tab!
Science as a Career
Science is a way of thinking, more than it is a body of knowledge.Carl Sagan
Nothing in life is to be feared, it is only to be understood.Marie Curie, Nobel Laureate 1903, 1911
Even though the ship may go down, the journey goes on.Margaret Mead